Advanced Dentistry & Aesthetics
Platelet Rich Fibrin (PRF) Treatment
PRF is a fibrin matrix that promotes skin rejuvenation, wound healing and hair growth. PRF is composed of platelet cytokines, growth factors and cells that work together to create a three-dimensional tissue matrix to aid in the healing of soft tissue and regeneration of joint cartilage.
What Is PRF?
To obtain PRF, we will first begin by drawing a standard blood sample which will then be placed in a centrifuge. The centrifuge spins and separates the various components of the blood. The result is three separate layers consisting of red blood cells on the bottom, the fibrin layer of PRF in the middle and low platelet plasma on top. The PRF is removed from the tube and prepared for treatment. Spin cycles and preparation vary depending on the intended use.
Who Is A Good Candidate For PRF Treatment?
PRF in Facial Esthetics
PRF Vs. PRP?
PRF is the next generation in the evolution of blood concentrates.
The number of platelets is far higher in PRF than in PRP. In PRP, the platelet count is approximately two to five times higher than in typical blood. PRF has a platelet concentration that is 10 times higher than normal blood.
Platelet-Rich Plasma (PRP):
PRP is spun at a high speed, causing many of the cells we wish to collect to be damaged and mixed with the other layers.
Blood that is collected in PRP requires an anticoagulant additive called acid citrate dextrose to keep blood from clotting too quickly. An anticoagulant is not needed for PRF.
Platelet-Rich Fibrin (PRF):
PRF is spun at a lower speed and has an even higher concentration of platelets, white blood cells, growth factors, and stem cells. This gives PRF more healing properties than PRP.
PRF not only has more growth factors but it releases them slower than PRP. This is an important distinction because while PRP reaches its highest amount of growth factors on the first day, and then declines rapidly afterward, PRF reaches its highest amount 14 days after injection, providing the body with a steady supply of growth factors. The benefit is analogous to having a drip line to water a plant, compared to dumping the same amount of water on the plant in one day.